Monday, January 24, 2011

Blood Sugar Control is Key to Prevent Diabetes and Chronic Disease


Humans did not evolve to metabolize the large amount of carbohydrate calories consumed by the most health conscious individuals today. High levels of blood glucose are a significant underlying factor that leads to the development and proliferation of many age-related diseases.
Diabetes, heart disease, stroke, cancer and dementia are all accelerated by slowly increasing fasting and post meal blood sugar levels that cause needless suffering and death for millions of unsuspecting people each year. Taking the necessary dietary and nutritional steps today can prevent the current explosion of new diabetes cases in the future and lengthen natural lifespan.


Redefining Healthy Blood Sugar Readings
Normal blood sugar levels have been continually revised downward over the past several decades as it`s determined that current levels cause cellular damage. Presently a fasting reading over 126 mg/dl repeated twice is considered cause for a diagnosis of diabetes.
A reading of 110 mg/dl or above is classified as impaired by the American Diabetes Association. Information published in the journal Diabetes Care indicates that a fasting blood glucose level above the range of 70 – 85 mg/dl dramatically increases the risk of developing heart disease and death from a heart attack. The researchers conclude “fasting blood glucose values in the upper normal range appears to be an important independent predictor of cardiovascular death in nondiabetic apparently healthy men.”


Excess Sugar Damages Vessel Walls, Leads to Insulin Resistance
Excess blood sugar triggers a cascade of potentially deadly processes that contribute to diabetes, hardening of the coronary arteries and neuropathic complications. High glucose levels from dietary sugar and excess carbohydrate consumption provokes the release of chemical cytokines that promote arterial wall inflammation, endothelial dysfunction and atherosclerosis. Eventually the pancreas is no longer able to secrete enough insulin, and the insulin that is produced is no longer able to efficiently escort sugar to the cells and muscles.




Naturally Lowering Blood Sugar with Diet
Nutrients such as cinnamon and vinegar taken before eating can help lower post meal blood sugar spikes and can compliment proper diet.
The most dependable way to naturally cut blood sugar levels is to dramatically lower calories from carbohydrate sources at each meal. Totally eliminate all processed and refined carb foods including bread, pasta, corn and rice.
Depending on carbohydrate sensitivity, some individuals may also need to limit fruits and starchy vegetables as well. The results of a study published in the Journal of the American College of Nutrition shows that a diet rich in monounsaturated fats such as the Mediterranean diet improves post meal blood glucose levels and moderates healthy insulin response.


High Protein, Low Carbohydrate Breakfast Regulates Blood Sugar
The result of 
research published in the journal Diabetes Care demonstrates the importance of including protein as part of a low carbohydrate breakfast. Participants were given a high protein food shortly before eating a low carb breakfast. Post meal blood sugar readings were 40% lower than the same meal eaten without the protein source in advance. This underscores the importance of combining proteins and monounsaturated fat sources with each meal to slow down the release of potentially damaging sugar surges.
The best way to protect yourself from out of control blood sugar spikes is to monitor your blood glucose at 1 and 2 hour intervals after eating. Avoid any reading above 140 mg/dl as tissue damage has been observed with sustained levels above this threshold. Research provides extensive evidence that controlling fasting and post meal blood sugar results in lower disease risk and lengthened lifespan.

via Technorati

Wednesday, January 19, 2011

Aspirin: Pain Reliever, Heart Attack Preventer & Possible Cancer Preventer Rolled into One Tablet



If you take aspirin, you've got a pain reliever, heart attack preventer and possible cancer preventer rolled into one tablet. You might think that whoever invented aspirin is a genius, but the truth is humans have been using its natural equivalent for thousands of years.
"Aspirin is one of those things that, long before there were ever clinical trials or any kind of scientific knowledge, people figured out, 'Hey, I feel better when I take this substance,' " said Dr. Karol Watson, assistant professor of cardiology at University of California, Los Angeles.
The drug has been making headlines because a study in the Lancet recently found that a daily aspirin appeared to lower the risk of cancer by at least 20% during a 20-year period. That's based on data from more than 25,000 patients and builds on earlier findings that aspirin may lower the risk of colorectal cancer. The research has limitations and is not definitive proof, but it does add another benefit to an ancient remedy that has been called a miracle drug.
"There are no countries in which it is unknown, unappreciated, or unavailable," the late medical writer Berton Roueché wrote in 1955, in an article later published in the anthology "The Medical Detectives."
History of aspirin
The word "aspirin" wasn't a coincidence. It comes from Spiraea, a biological genus of shrubs that includes natural sources of the drug's key ingredient: salicylic acid. This acid, resembling what's in modern-day aspirin, can be found in jasmine, beans, peas, clover and certain grasses and trees.
The ancient Egyptians used willow bark as a remedy for aches and pains, said Diarmuid Jeffreys, author of "Aspirin: The Remarkable Story of a Wonder Drug." They didn't know that what was reducing body temperature and inflammation was the salicylic acid.
It wasn't until thousands of years later that people began to isolate the key ingredients of aspirin. An 18th-century clergyman, Edward Stone, rediscovered aspirin, in effect, when he wrote a report about how a preparation of powdered willow bark seemed to benefit 50 patients with ague and other maladies, Roueché wrote.
Aspirin's uses for heart patients came to light in 1948 when California physician Dr. Lawrence Craven recommended an aspirin a day to reduce heart attack risk, based on what he had observed in patients.
The Nobel Prize in medicine in 1982 was awarded to researchers who demonstrated the reason -- it inhibits production of hormones called prostoglandins. Prostoglandins are responsible for the formation of clots that leads to heart attacks and strokes, and aspirin prevents that clotting from happening.
Toward better preventative medicine
Today, aspirin is universally recognized as heart-attack prevention in men who have had prior heart attacks, and it has also shown to have benefits against stroke in women.
More than 1/3 of all adults, and 4 out of 5 people with heart disease, use aspirin regularly, according to data from the Centers for Disease Control and Prevention presented in a 2006 study. And the number of regular aspirin users rose 20% from 1999 to 2003.
Still, it's not necessarily the go-to for over-the-counter painkillers. In 2007, pain relievers such as Advil, Tylenol and Aleve were among the top five analgesics sold; aspirin did not make the cut.
"If you're hurting, you're going to reach for a stronger pain reliever," Watson said. "In most cases, a baby aspirin a day is not going to make you feel any better or worse."
The U.S. Preventive Services Task Force recommends that men 49 to 79 take aspirin to prevent heart attack, and that women 55 to 79 take it to guard against ischemic strokes, when the potential benefits outweigh the potential harms from an increase in gastrointestinal hemorrhage. In other words, aspirin can increase bleeding because of decreased clotting, so if you have bleeding problems, it's not a good idea.
Aspirin's potential cancer benefits have come on the scene more recently, and there aren't standard guidelines in that regard. The agency discourages taking aspirin to prevent colorectal cancer in people with average risk for that disease. Also, the mechanism isn't entirely understood, although the thought is that aspirin helps the body cut off blood supply to cancer growths, Jeffreys said..
Patients should not just take it without consulting their physicians, Fishman said. Certain conditions such as bleeding disorders make taking aspirin dangerous. Some supplements, such as fish oil and garlic, can also cause bleeding problems in combination with aspirin, he said. Aspirin is not approved for children younger than 2 and should be used with caution in very young people because of apossible link to Reye's syndrome.
Still, it's likely that aspirin has even more benefits that just haven't been discovered yet, Jeffreys said. In his view, the drug is taken for granted, and not enough emphasis is placed on it.
"If I'm stranded on a desert island, and I can take one drug with me, that's the one I'm taking," Watson said.

Monday, January 17, 2011

Ever wondered how hormones work?

 

What the hormone system is

The hormone system is a network of glands and organs in the body that produce hormones. It is also called the endocrine system. The main parts of the hormone system are shown in the diagram below.
Diagram showing the hormone system
 

Hormones and how they work

Hormones are natural substances made by the glands and organs of the hormone system. Our bloodstream carries the hormones around the body. Each gland makes a different hormone and most make more than one.
There are many different hormones. Each only works on the particular cells that are able to receive and respond to that hormone’s message. So they act as chemical messengers between one part of the body and another.
Each hormone has a different purpose. Generally speaking, they control how we respond to changes in the environment around us, as well as
  • Growth and development
  • How the body works
  • Our mood
  • Sexual function
  • Reproduction
After a hormone is released, it travels from the gland to its target cells through the bloodstream. It connects to a part of the target cell called a receptor. The connection triggers a response in the cell. The type of response depends on the type of hormone.
In the brain, the hypothalamus and the pituitary gland control the whole hormone system and levels of hormones in the body.
 

The hypothalamus and hormone level control

The hypothalamus is part of the brain and not actually part of the endocrine system.
brain_parts_1
The hypothalamus works with the pituitary gland to control the activity of most of the other glands of the endocrine system. It reacts to changes in the amount of hormones in the body. When the level of a particular hormone drops below what it should be, the hypothalamus signals to the pituitary gland. The pituitary then produces hormones that tell other organs to produce the hormone that the body needs.
For example, the thyroid gland makes thyroid hormones. It only does this when the hypothalamus detects that the level of thyroid hormones is low. The hypothalamus signals to the pituitary gland to produce thyroid stimulating hormone (TSH). TSH stimulates the thyroid to produce thyroid hormones. When the thyroid hormones are at the right level, the hypothalamus signals to the pituitary gland to stop producing TSH. The thyroid gland then stops making thyroid hormones. This system is called a negative feedback mechanism and is how the body controls hormone levels.
 

The pituitary gland

This is a small gland on the under surface of the brain. It makes a number of hormones and controls many different body functions. Many of the pituitary gland hormones signal to other parts of the hormone system to make, or stop making, other hormones.
Pituitary hormones control
  • Growth, by producing growth hormone
  • The speed of body processes (metabolism) - thyroid stimulating hormone (TSH) tells the thyroid gland to make thyroid hormones
  • Steroid levels - adrenocorticotropic hormone (ACTH) tells the adrenal glands to make steroids
  • Breast milk production after birth - prolactin makes the breasts produce milk
  • Periods and egg production in women
  • Sperm and testosterone production in men
Egg and sperm production are controlled by two pituitary hormones, follicle stimulating hormone (FSH) and luteinising hormone (LH). These control oestrogen and progesterone levels in women and testosterone levels in men. FSH and LH levels are in turn controlled by the hypothalamus.
 

The pineal gland

The pineal gland is a very small gland deep in the brain. It makes the hormone melatonin, which controls sleep patterns. You can see the position of the pineal gland in the diagram above.
 

The thyroid and parathyroid glands

The thyroid gland is at the base of the neck. You can see the position of the thyroid and parathyroid glands in the diagram above. The thyroid makes these hormones
  • T3 - also called tri iodothyronine
  • T4 - also called thyroxine
  • Calcitonin
The hormones T3 and T4 help to control how fast your body works – your metabolic rate. If your thyroid gland doesn’t make enough of these hormones, you put on weight and feel very tired and lacking in energy.
If your thyroid gland makes too much of the T3 and T4 hormones, you lose weight and have an increased appetite. With an overactive thyroid you may also feel anxious and find it difficult to relax.
Calcitonin helps to control the amount of calcium in the body.
There are 4 parathyroid glands. They are very small glands at the base of your neck very close to the thyroid gland. They make parathyroid hormone (PTH). Along with calcitonin and vitamin D, PTH controls the level of calcium in the body.
 

The adrenal glands

You have two adrenal glands - one above each kidney. They make several hormones. Cortisol is a natural steroid hormone that affects the level of sugar in the blood. Aldosterone helps to regulate the body’s water and salt balance, and the blood pressure.
The adrenal glands also produce small amounts of the male and female sex hormones (oestrogen and testosterone).
Probably the best known hormone made in the adrenal gland is adrenalin (epinephrine), which helps us to respond quickly when under stress. Another similar hormone, noradrenalin (norepinephrine), also helps us to respond quickly under stressful conditions.
 

The pancreas

The pancreas is quite high up in your abdomen. It lies across the body, where your ribs meet at the bottom of your breastbone, just behind your stomach. You can see the position of the pancreas in the diagram above. It is about 6 inches long and shaped like a leaf. The pancreas makes insulin, which controls the amount of sugar in our blood. It also makes other hormones that help with digestion, including glucagon, somatostatin and pancreatic polypeptide.
 

The ovaries

The ovaries produce 2 sex hormones, oestrogen and progesterone. Together they control the menstrual cycle (periods).
During puberty oestrogen helps the development of female sexual characteristics, including breast growth and the maturing of the womb (uterus) and vagina.
Progesterone plays a part in maintaining pregnancy.
 

The testes

The testicles or testes produce the hormone testosterone. Testosterone gives male qualities such as a deep voice and beard growth. It also controls sex drive (libido), the ability to have an erection.

Friday, January 14, 2011

Use of Breast MRI Results in High Cancer Detection (via @CBCCmiami )

(**as offered in our Digital Medical Imaging offices through Total Body Scan)

Scientists have found that the use of preoperative breast MRI detects otherwise occult cancer with a relatively high degree of accuracy when applied to a diverse population of patients newly diagnosed with breast cancer.

The study was performed at the University of Washington and Seattle Cancer Care Alliance in Seattle, WA.
The review initiated with 592 patients who were recently diagnosed with breast cancer and underwent staging with preoperative breast MRI.

The analysis set was comprised of 570 patients, whose biopsy rates, positive predictive values (PPVs) of biopsy, and overall cancer yields were calculated and compared using the chi-square test across patient age, breast density, index tumor type, receptor status and lymph node status.

“Our data add to the growing body of literature that documents breast MRI’s ability to detect otherwise occult additional disease in patients who have been newly diagnosed with breast cancer,” said Robert Gutierrez, lead author of the study.

We found that use of preoperative breast MRI in newly diagnosed cancer patients resulted in an added cancer yield of 12%.This is much higher than the added cancer yield of .08 to 6.7p%seen with high risk screening breast MRI, a more widely accepted indication for breast MRI, ” said Gutierrez.

The study appeared in the January 2011 issue of the American Journal of Roentgenology. (ANI)

Wednesday, January 12, 2011

Teens with High Sugar Diet Up their Risk of Heart Disease

Excessive intake of sugar-sweetened beverages like soft drinks and fruit juices that offer no nutritional value other than calories to the diet of teenagers can elevate their risk of heart disease in later life, claims a new study.
According to health experts, there is growing evidence of the link between excess sugar consumption among youngsters and a number of health conditions such as obesity, hypertension, elevated triglycerides that are considered markers for heart disease.
Lead author of the study, Jean Welsh, post-doctoral fellow at Emory University School of Medicine in Atlanta stated, "We need to be aware of sugar consumption. It's a significant contributor of calories to our diet and there are these associations that may prove to be very negative. Sugar-sweetened soft drinks and sodas are the major contributor of added sugar and are a major source of calories without other important nutrients."
"Parents and adolescents need to become aware of the amount of added sugar they are consuming and be aware that there may be some negative health implications if not now, then down the line.”
AHA Recommendations
According to the American Heart Association (AHA) recommendations, a teenager who requires 2,200 calories may have an upper limit of 150 calories from added sugar while someone with an energy requirement of 1,800 calories per day should limit added sugar to 100 calories.
However, the National Health and Nutrition Survey (NHANES) of 2,157 teenagers aged 12 to 18 years found that the average teenager consumes close to 500 calories added sugars each day. "Adolescents are eating 20% of their daily calories in sugars that provide few if any other nutrients," said Jean Welsh.
Study Details
In order to get an insight into the impact of high sugar consumption in adolescence on the risk of cardiovascular disease in later life the researchers studied 646 teenagers.
For the purpose of the study, they analyzed the 24-hour dietary recall by teens with data from the US Department of Agriculture on sugar content in foods.
It was noted that the teens’ average daily consumption of added sugars was three to five times higher that the limit acceptable by the American Heart Association.
The study found, that teens who consumed 30% or more of total calories from added sugars exhibited... higher levels of triglycerides and LDL or “bad” cholesterol, compared to those who ate less than 10 percent of added sugar. In addition, it was observed that obese and overweight teenagers who consumed more sugar also had the most insulin resistance.
Need for more Research
Although the study hints at a possible association between added sugar intake and poor cholesterol profiles as well as other heart disease risk factors, researchers feel there is need for more research to substantiate the findings.
Welsh stated, “We need controlled studies to really understand the role of added sugars in cardiovascular disease. But it is important to be aware of the added sugar in the foods we all eat.”
The study is published in the American Heart Association (AHA) journal 'Circulation via the Med Guru